is there any relationship between hyperglycemia ....
赵灵1
珠海市人民医院ICU场
Objective:This study aimedto better understand the relationship between hyperglycemia and outcome after traumatic diffuse axonal injury(TDAI).
Methods: we prospectively studied 192 patients with moderate or severe TDAI(Glasgow Coma Scale scores, 3-12) who were treated conservatively in the general intensive care unit of zhuhai hospital between January 2000 and December 2009. Serum glucose, GCS and GOS of all the patients were measured: serum glucose, GCS score was recorded on admission, on days 3, 7 and 2 weeks ; Outcome was determined by Glasgow Outcome Scale (GOS) score at discharge and after 3 months , respectively and the data were analyzed statistically to determine the relationship between serum glucose levels, severity of injury, and neurological outcome.
Results: Patients who died had significantly higher admission serum glucose values than those patients who survived (230mg/dL vs. 130mg/dL;P<0.005). Admission serum glucose> or =210mg/dL was uniformly associated with a worse outcome. Admission Glasgow Coma Scale score and serum glucose are independent predictors of mortality in patients with TDAI.
Conclusions: Early hyperglycemia is a a significant indicator of its severity, and a reliable predictor of outcome to TDAI.
Methods: we prospectively studied 192 patients with moderate or severe TDAI(Glasgow Coma Scale scores, 3-12) who were treated conservatively in the general intensive care unit of zhuhai hospital between January 2000 and December 2009. Serum glucose, GCS and GOS of all the patients were measured: serum glucose, GCS score was recorded on admission, on days 3, 7 and 2 weeks ; Outcome was determined by Glasgow Outcome Scale (GOS) score at discharge and after 3 months , respectively and the data were analyzed statistically to determine the relationship between serum glucose levels, severity of injury, and neurological outcome.
Results: Patients who died had significantly higher admission serum glucose values than those patients who survived (230mg/dL vs. 130mg/dL;P<0.005). Admission serum glucose> or =210mg/dL was uniformly associated with a worse outcome. Admission Glasgow Coma Scale score and serum glucose are independent predictors of mortality in patients with TDAI.
Conclusions: Early hyperglycemia is a a significant indicator of its severity, and a reliable predictor of outcome to TDAI.
