目的：探讨慢性阻塞性肺疾病和支气管哮喘生理评分（The COPD and Asthma Physiology Score，CAPS）在慢性阻塞性肺疾病急性加重期（AECOPD）伴呼吸衰竭患者中的应用价值。方法：回顾性的分析我科2005年1月至2009年3月收治的82例AECOPD伴呼吸衰竭患者的临床资料，分别计算CAPS、APACHEⅡ和APACHEⅢ评分，然后进行统计学处理与分析。结果：死亡组和存活组CAPS、APACHEⅡ评分、APACHEⅢ评分分别为34.21±9.89、27.41±8.15；22.53±7.49、18.65±5.34；75.11±18.07、64.11±15.92；25.06±24.64、5.23±5.50；32.42±25.49、12.51±20.70，组间差异均有显著性（P均＜0.05）。CAPS、APACHEⅡ和APACHEⅢ评分ROC曲线下面积分别是0.712 （P=0.005）、0.654（P=0.043）和0.655(P=0.042)，CAPS评分30.5时Youden指数最大，为0.435。CAPS评分超过30分时死亡率明显增加。 结论：CAPS对AECOPD伴呼吸衰竭患者病情的评估与预后的判断具有良好的效果，且优于APACHEⅡ和APACHEⅢ，简单依从性好，值得临床推广应用。、有创通气时间（天）、住ICU时间（天）

 The value of CAPS in prognostic assessment of patients with AECOPD combined with typeⅡchronic respinary failure

ZHANG Mu-cheng，WANG Zheng-guang，CHENG Jin-xia， WANG Jian-lei，ZHEN Shao-peng

ICU，People’s Hospital of Huangshan Affilated Wannan Medical College，Huangshan 245000，China

[Abstract] Objective to explore the value of the COPD and Asthma Physiology Score(CAPS）in patients with AECOPD combined with typeⅡrespiratory failure. Methods 82 cases of AECOPD combined with typeⅡrespiratory failure from January 2005 to March 2009 were admitted, retrospective and statistical analyses of the data from all cases were performed. Results CAPS，APACHEⅡscores，APACHEⅢ scores，duration of IPPV and duration of hospitalization of died group and survival group were 34.21±9.89、27.41±8.15；22.53±7.49、18.65±5.34；75.11±18.07、64.11±15.92；25.06±24.64、5.23±5.50；32.42±25.49、12.51±20.70 respectively，there were significant difference in two groups（P＜0.05）.The mortality was up as the CAPS increased, the mortality increased remarkably when the score was ≥30.the cut-off was 30.ConclusionAPACHEⅡand APACHEⅢ.It was easy to perform and worthy of being recommended to give further clinic application. CAPS was very effective to evaluate the severity and prognosis of patients, better than